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  3. CELF5 - CUGBP Elav-like family member 5 Gene

CELF5 - CUGBP Elav-like family member 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CELF-5; BRUNOL5; BRUNOL-5

Gene ID: 60680 | Gene type: protein coding

About CELF5

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:3,224,661-3,297,076 (from NCBI)

This gene has 8 transcripts (splice variants), 183 orthologues and 6 paralogues. Biased expression in brain (RPKM 14.1), ovary (RPKM 2.1) and 1 other tissue.

Summary

This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

CELF5 Products(2)

mRNA Protein Name
NM_001172673.2 NP_001166144.1 CUGBP Elav-like family member 5 isoform 2
NM_021938.4 NP_068757.2 CUGBP Elav-like family member 5 isoform 1

CELF5 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (47 - 113)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (136 - 198)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (402 - 471)

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  • 485 a.a.
Protein Preferred Names Protein Names

CUGBP Elav-like family member 5

CUG-BP and ETR-3 like factor 5

Related Diseases

Diseases Alias
Specific Language Impairment

Language Impairment, Specific
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02463 CELF5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CELF5 VGNC VGNC:60747
Mus musculus CELF5 MGD MGI:2442333
Rattus norvegicus CELF5 RGD RGD:1565016
Canis familiaris CELF5 VGNC VGNC:39096
Bos taurus CELF5 VGNC VGNC:55204
Macaca mulatta CELF5 VGNC VGNC:109597