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No matches for "

93474

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6

Inhibitors & Agonists

5

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156906
    UNC3474

    		MDM-2/p53 Cancer
    UNC3474 is a small molecule ligand, binding with 53BP1. UNC3474 binds the aromatic methyl-lysine binding cage of 53BP1 TT, with a dissociation constant (Kd) of 1.0 ± 0.3 μM. UNC3474 inhibits the recruitment of 53BP1 to DSBs by stabilizing a pre-existing autoinhibited state of 53BP1 in cells .
    UNC3474
  • HY-142090
    Donetidine

    SK&F 93574

    		 Histamine Receptor Others
    Donetidine (SK&F 93574) is an antagonist for histamine H2 receptor, that promotes histamine release in beagle dog models .
    Donetidine
  • HY-R03073
    mmu-miR-3474 mimic

    		MicroRNA Cancer
    mmu-miR-3474 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-3474 mimic
    mmu-miR-3474 mimic
  • HY-RI03073
    mmu-miR-3474 inhibitor

    		MicroRNA Cancer
    mmu-miR-3474 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-3474 inhibitor
    mmu-miR-3474 inhibitor
  • HY-RI03073A
    mmu-miR-3474 antagomir

    		MicroRNA Cancer
    mmu-miR-3474 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-3474 antagomir
    mmu-miR-3474 antagomir
  • HY-R03073A
    mmu-miR-3474 agomir

    		MicroRNA Cancer
    mmu-miR-3474 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-3474 agomir
    mmu-miR-3474 agomir

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