CDX2 - caudal type homeobox 2 Gene

Also Known as CDX3; CDX-3; CDX2/AS

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 1045

About CDX2

Cytogenetic location: 13q12.2 Genomic coordinates (GRCh38): 13:27,960,918-27,969,315 (from NCBI)

This gene has 2 transcripts (splice variants), 129 orthologues, 2 paralogues and is associated with 43 phenotypes. Biased expression in colon (RPKM 23.4), small intestine (RPKM 15.9) and 2 other tissues.

Summary

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]

CDX2 Products (2)

mRNA	Protein	Name
NM_001265.6	NP_001256.4	homeobox protein CDX-2 isoform 1
NM_001354700.2	NP_001341629.1	homeobox protein CDX-2 isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	15677472	GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	15677472	GOA
enables methyl-CpG binding	IDA IDA: Inferred from direct assay	28473536	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	15677472	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDX2 Protein Structure

Caudal_act

Homeobox

0
100
200
313 a.a.

Protein Preferred Names	Protein Names
homeobox protein CDX-2	caudal type homeobox transcription factor 2

CDX2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CDX2	Q99626	KRTAP4-12	Homo sapiens	Q9BQ66	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

CDX2 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80983	CDX2 Antibody (YA3498)	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
HY-P84754	CDX2 Antibody (YA4451)	IHC-P, FC, ELISA	Human
HY-P84754A	CDX2 Antibody (YA4451)(PBS only)	IHC-P, FC, ELISA	Human
HY-P85569	CDX2 Antibody (YA5261)	WB, IP, ICC/IF	Human, Monkey
HY-P85655	CDX2 Antibody (YA5347)	WB, ICC/IF, IHC-P	Human, Mouse, Rat
HY-P85796	CDX1+CDX2+CDX4 Antibody (YA5488)	IHC-P, ICC/IF, ELISA	Human
HY-P86008	CDX1+CDX2+CDX4 Antibody (YA5700)	IHC-P, ICC/IF, ELISA	Human

Related Diseases

Diseases	Alias
Sirenomelia	Fused Legs And Feet Mermaid Malformation Mermaid Syndrome Sirenomelia Sequence Sirenomelus Sirenomelia Syndrome
Pseudomyxoma Peritonei	Adenomucinosis Gelatinous Ascites Pmp Mucinous Ascites Syndrome Of Pseudomyxoma Peritonei
Tubular Adenocarcinoma	Tubular Carcinoma Adenocarcinoma Tubular Adenocarcinoma, Tubular
Barrett Esophagus	Barrett'S Esophagus Barrett Esophagus/Esophageal Adenocarcinoma Barrett Metaplasia Barrett'S Ulcer Of Esophagus Ulcerative Esophagitis Barrett'S Esophagus With Esophagitis Barrett'S Oesophagus Barretts Syndrome Barrett Syndrome BE Peptic Ulcer Of Esophagus Adenocarcinoma Of Esophagus
Bladder Adenocarcinoma	Adenocarcinoma Of Bladder Adenocarcinoma Of The Urinary Bladder Bladder Adenocarcinoma, Not Otherwise Specified Adenocarcinoma Bladder
Cervical Adenocarcinoma	Adenocarcinoma Cervix Uteri Adenocarcinoma Of Cervix Adenocarcinoma Of The Uterine Cervix Adenocarcinoma Of The Cervix Uteri
Ampulla Of Vater Cancer	Ampulla Of Vater Carcinoma Ampullary Carcinoma Malignant Tumour Of Ampulla Of Vater Carcinoma Of Ampulla Of Vater Carcinoma Of The Ampulla Of Vater Ampulloma
Appendix Disease	Disorder Of Appendix
Atrophic Gastritis	Gastritis, Atrophic Gastric Atrophy Gastritis Atrophic
Appendix Adenocarcinoma	Cystadenocarcinoma Mucinous Adenocarcinoma Adenocarcinoma Of Appendix Appendiceal Adenocarcinoma Adenocarcinoma Of The Appendix Colonic Type Adenocarcinoma Nonmucinous Adenocarcinoma
Anus Adenocarcinoma	Adenocarcinoma Of Anus Adenocarcinoma Of The Anus
Duodenum Adenocarcinoma	Duodenal Adenocarcinoma
Jejunal Adenocarcinoma
Ovarian Seromucinous Carcinoma	Mixed Epithelial Carcinoma Of Ovary Ovary Mixed Epithelial Carcinoma
Thymus Adenocarcinoma	Adenocarcinoma Of The Thymus Thymic Adenocarcinoma
Jejunal Cancer	Jejunal Neoplasms Malignant Neoplasm Of Jejunum Malignant Tumor Of Jejunum
Small Intestine Adenocarcinoma	Small Intestinal Adenocarcinoma Adenocarcinoma Of Small Intestine Adenocarcinoma Of The Small Bowel Adenocarcinoma Of Small Bowel Adenocarcinoma Of Small Instestine Adenocarcinoma Of The Small Instestine Small Bowel Adenocarcinoma Adenocarcinoma Of The Small Intestine
Microinvasive Gastric Cancer	Early Gastric Cancer Surface Gastric Cancer
Ovary Neuroendocrine Neoplasm	Neuroendocrine Tumor Of Ovary
Benign Teratoma	Dermoid Cyst Cystic Dermoid Choristoma Dermoid Choristoma Mature Cystic Teratoma Dermoid Tumour Teratoma, Benign Dermoid Cyst Of Ovary
Appendix Cancer	Appendiceal Neoplasms Cancer Of The Appendix Malignant Neoplasm Of Appendix Vermiformis Malignant Tumor Of Appendix Malignant Tumor Of The Appendix Malignant Neoplasm Of Appendix Carcinoma Of The Appendix
Ovarian Mucinous Neoplasm	Ovarian Mucinous Tumor Malignant Ovarian Mucinous Neoplasm Mucinous Tumor Of Ovary Malignant Ovarian Mucinous Tumor
Pancreatic Foamy Gland Adenocarcinoma
Ethmoid Sinus Adenocarcinoma	Adenocarcinoma Of Ethmoid Sinus Adenocarcinoma Of The Ethmoid Sinus
Intestinal Obstruction	Inspissated Milk Syndrome Milk Curd Syndrome
Small Intestine Cancer	Small Intestine Carcinoma Cancer Of The Small Bowel Small Bowel Cancer Small Intestinal Carcinoma Malignant Neoplasms Of The Small Intestine Small Bowel Tumors Malignant Tumor Of Small Intestine Neoplasm Of Small Intestine
Bladder Signet Ring Cell Adenocarcinoma	Signet Ring Cell Adenocarcinoma Of Bladder Urinary Bladder Signet Ring Adenocarcinoma
Krukenberg Carcinoma	Krukenberg Tumor Krukenberg Neoplasm Krukenberg'S Tumor
Mucinous Adenocarcinoma	Mucin-Producing Adenocarcinoma Mucin-Secreting Adenocarcinoma Mucin-Secreting Carcinoma Mucous Carcinoma Pseudomyxoma Peritonei With Unknown Primary Site Adenocarcinoma, Mucinous
Anal Canal Carcinoma	Anal Canal Cancer Anal Canal And Perianal Gland Carcinoma Carcinoma Of The Anal Canal Carcinoma Of Anal Canal
Ovarian Mucinous Adenocarcinoma	Mucinous Carcinoma Of Ovary
Anal Canal Adenocarcinoma	Adenocarcinoma Of The Anal Canal Adenocarcinoma Of Anal Canal
Anal Paget'S Disease	Anal Paget Disease Paget'S Disease Of Anus Paget'S Disease Of The Anus Paget Disease Of The Anus
Cystitis Cystica
Bronchiolo-Alveolar Adenocarcinoma	Bronchioloalveolar Carcinoma Bronchioalveolar Lung Carcinoma Minimally Invasive Lung Adenocarcinoma Carcinoma Bronchioloalveolar Adenocarcinoma, Bronchiolo-Alveolar Bronchioloalveolar Adenocarcinoma
Mucinous Intrahepatic Cholangiocarcinoma	Mucin-Producing Intrahepatic Cholangiocarcinoma
Gastritis	Acute Gastric Mucosal Erosion Erosive Gastritis Erosive Gastropathy Gastritis Erosive Idiopathic Erosive/Hemorrhagic Gastritis Inflammation Of Gastric Mucosa Gastroduodenitis Gastritis Nos Noninfectious Gastroenteritis Nonbacterial Gastroenteritis Of Infant Acute Gastric Infection Acute Simple Gastritis Chronic Antral Gastritis Chronic Fundal Gastritis Chronic Simple Gastritis Acute Gastroduodenitis Acute Antral Gastritis Acute Erosive Gastritis Bile Reflux Gastritis Gastritis Due To Biliary Reflux
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Gallbladder Carcinoma In Situ
Ampulla Of Vater Adenocarcinoma	Adenocarcinoma Of Ampulla Of Vater Ampullary Adenocarcinoma
Periampullary Adenocarcinoma
Teratoma	Teratomas
Bladder Urachal Carcinoma	Urachal Cancer Urachal Carcinoma
Urachus Cancer	Malignant Tumor Of Urachus
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Gastric Adenocarcinoma	Adenocarcinoma Of Stomach Stomach Adenocarcinoma Adenocarcinoma Gastric Intestinal Type Adenocarcinoma Of Unspecified Site Diffuse Type Adenocarcinoma Of Unspecified Site
Glandular Cystitis	Cystitis Glandularis
Gastric Diffuse Adenocarcinoma	Diffuse Gastric Adenocarcinoma Carcinoma, Diffuse Type
Appendiceal Neoplasm	Appendix Neoplasm Neoplasm Of Appendix Appendiceal Neoplasms Appendiceal Cancer Appendix Cancer Malignant Neoplasm Of Appendix Vermiformis Malignant Tumour Of Appendix
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Laryngeal Mucoepidermoid Carcinoma	Mucoepidermoid Carcinoma Of Larynx
Adenoma	Acinar Cell Adenoma Adenomas Acinic Cell Adenoma
Gallbladder Adenocarcinoma	Adenocarcinoma Of The Gallbladder Carcinoma Of The Gallbladder
Cystic Teratoma	Dermoid Cyst Benign Teratoma
Gallbladder Cancer	Gallbladder Carcinoma Gallbladder Neoplasm Malignant Neoplasm Of Gallbladder Malignant Tumour Of Gallbladder Gallbladder Ca Localized Malignant Gallbladder Neoplasm Malignant Tumor Of The Gallbladder Tumor Of The Gallbladder Cancer Of The Gallbladder Carcinoma Gallbladder Carcinoma Of Gallbladder Gallbladder Neoplasms Malignant Neoplasm Of Gallbladder Localized Cancer Of Gallbladder Primary Malignant Neoplasm Of Gallbladder
Duodenum Cancer	Duodenal Cancer Duodenal Neoplasms Cancer Of Duodenum Duodenal Neoplasm Duodenal Carcinoma Cancer, Duodenal Malignant Neoplasm Of Duodenum
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease
Cecum Carcinoma	Cecum Cancer Caecum Carcinoma Carcinoma Of Cecum Cecal Cancer Malignant Neoplasm Of Caecum Malignant Tumor Of The Cecum
Mucinous Adenofibroma
Anal Gland Adenocarcinoma	Adenocarcinoma Of Anal Ducts Adenocarcinoma Of Anal Gland Anal Glands Adenocarcinoma Adenocarcinoma Of Anal Glands
Colloid Carcinoma Of The Pancreas
Bile Duct Cancer	Bile Duct Carcinoma Extrahepatic Bile Duct Carcinoma Carcinoma Of Extrahepatic Bile Duct Extrahepatic Bile Duct Cancer Bile Duct Neoplasms Bile Duct Tumor Ca Extrahepatic Bile Ducts Malignant Neoplasm Of The Extrahepatic Bile Duct Bile Duct Extrahepatic Carcinoma Malignant Tumor Of Extrahepatic Bile Duct
Signet Ring Cell Adenocarcinoma	Signet Ring Cell Carcinoma Carcinoma, Signet Ring Cell Signet Ring Carcinoma Carcinoma Signet Ring Cell
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Bile Reflux
Ethmoid Sinus Cancer	Malignant Neoplasm Of Ethmoidal Sinus Malignant Tumor Of Ethmoid Sinus Malignant Tumor Of Ethmoidal Sinus Neoplasm Of Ethmoidal Sinus
Vaginal Tubulovillous Adenoma
Duodenum Disease	Duodenal Diseases Duodenal Disease Duodenum Disorder
Nasal Cavity Cancer	Nasal Cavity Carcinoma Malignant Neoplasm Of Nasal Cavities Malignant Tumor Of The Nasal Cavity Cancer Of Nasal Cavity Carcinoma Of Nasal Cavity Malignant Neoplasm Of Nasal Cavity Neoplasm Of Nasal Cavity
Nasal Cavity Adenocarcinoma	Adenocarcinoma Of Nasal Cavity Adenocarcinoma Of The Nasal Cavity
Benign Ileal Neoplasm	Ileal Tumor Ileal Neoplasms Ileal Neoplasm
Villous Adenoma	Adenoma Villous Adenoma, Villous
Mucinous Ovarian Cystadenoma	Mucinous Cystadenoma Of Ovary Ovarian Mucinous Cystadenoma
Ascending Colon Cancer	Malignant Tumor Of Ascending Colon Ca Ascending Colon Malignant Neoplasm Of Right Colon Malignant Neoplasm Of Ascending Colon
Neuroendocrine Tumor	Neuroendocrine Neoplasm Neuroendocrine Tumors Carcinoma, Neuroendocrine
Hepatoid Adenocarcinoma
Seminal Vesicle Adenocarcinoma
Linitis Plastica	Leather-Bottle Stomach
Anal Canal Paget'S Disease	Anal Canal Paget Disease Paget'S Disease Of Anal Canal Paget'S Disease Of The Anal Canal Paget Disease Of The Anal Canal
Rectum Neuroendocrine Neoplasm	Neuroendocrine Tumor Of Rectum Neuroendocrine Tumor Of The Rectum Net Of The Rectum Rectal Net Rectal Neuroendocrine Tumor Rectal Neuroendocrine Neoplasm
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Cholangiocarcinoma	Cholangiocarcinoma, Susceptibility To Extrahepatic Cholangiocarcinoma Intrahepatic Cholangiocarcinoma Chlc Chlc, Susceptibility To Cc Cholangiocarcinoma Of Biliary Tract Cholangiocellular Carcinoma Distal Cholangiocarcinoma Perihilar Cholangiocarcinoma Bile Duct Cancer Cca Adult Primary Cholangiocellular Carcinoma Bile Duct Carcinoma
Barrett'S Adenocarcinoma	Barrett Adenocarcinoma Adenocarcinoma Arising In Barrett'S Mucosa
Esophageal Adenosquamous Carcinoma
Meckel Diverticulum	Meckel'S Diverticulum Persistent Vitelline Duct
Gastric Signet Ring Cell Adenocarcinoma	Signet Ring Cell Gastric Adenocarcinoma Signet Ring Cell Adenocarcinoma Of The Stomach
Sigmoid Neoplasm	Sigmoid Neoplasms Neoplasm Of Sigmoid Colon Tumor Of Sigmoid Colon
Chronic Cystitis
Vulva Adenocarcinoma	Adenocarcinoma Of The Vulva Adenocarcinoma Of Vulva
Bladder Clear Cell Adenocarcinoma	Bladder Mesonephric Adenocarcinoma Clear Cell Adenocarcinoma Of Bladder
Vaginal Adenoma
Mucinous Bronchioloalveolar Adenocarcinoma	Bronchiolo-Alveolar Carcinoma, Mucinous
Medullary Colon Carcinoma
Colorectal Adenocarcinoma	Adenocarcinoma Of Large Intestine
Sublingual Gland Adenoid Cystic Carcinoma
Aortic Malignant Tumor	Aortic Malignant Neoplasm Malignant Aortic Neoplasm
Biliary Papillomatosis	Bile Duct Papillomatosis
Paget Disease, Extramammary	Extramammary Paget Disease Cutaneous Paget'S Disease Extramammary Paget'S Disease Paget Disease Extramammary Cutaneous Paget Disease Paget'S Disease Of Skin Empd Extramammary Pagets Disease
Breast Hemangioma	Angioma Of The Breast Hemangioma Of Breast Haemangioma Of Breast
Ureter Adenocarcinoma	Adenocarcinoma Of Ureter Ureteral Adenocarcinoma
Mucinous Cystadenocarcinoma	Cystadenocarcinoma, Mucinous Pseudomucinous Cystadenocarcinoma Cystadenocarcinoma Mucinous
Atypical Polypoid Adenomyoma
Descending Colon Cancer	Ca Descending Colon Malignant Neoplasm Of Left Colon Malignant Tumor Of Descending Colon Malignant Neoplasm Of Descending Colon
Nasal Cavity Olfactory Neuroblastoma	Olfactory Neuroblastoma Of The Nasal Cavity
Adenosquamous Colon Carcinoma	Adenosquamous Carcinoma Of Colon Colonic Adenosquamous Carcinoma Colon Adenosquamous Carcinoma
Peptic Esophagitis	Reflux Esophagitis Peptic Reflux Disease Reflux Oesophagitis Esophagitis, Peptic Gastro-Esophageal Reflux Disease With Esophagitis
Small Intestine Benign Neoplasm	Neoplasm Of Small Intestine Small Intestinal Neoplasm Neoplasm Of The Small Intestine Small Bowel Cancer Small Intestine Cancer Malignant Neoplasm Of Small Intestine, Unspecified Malignant Tumour Of Small Bowel Malignant Tumour Of Small Intestine Primary Malignant Neoplasm Of Meckel Diverticulum
Testicular Yolk Sac Tumor	Testicular Yolk Sac Neoplasm Endodermal-Sinus Tumor Orchidoblastoma Yolk Sac Tumor
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Vaginal Benign Neoplasm
Rectosigmoid Junction Neoplasm	Neoplasm Of Rectosigmoid Junction Rectosigmoid Neoplasm Rectosigmoid Tumor Rectosigmoid Carcinoma Carcinoma Of The Rectosigmoid Junction Malignant Tumor Of Rectosigmoid Junction Rectosigmoid Junction Cancer Primary Malignant Neoplasm Of Rectosigmoid Junction Rectosigmoid Colon Cancer Carcinoma Of Rectum With Sigmoid Colorectal Cancer Nos Colorectal Carcinoma Nos Rectosigmoid Cancer
Urinary Bladder Villous Adenoma	Villous Adenoma Of Urinary Bladder Bladder Villous Adenoma
Sublingual Gland Cancer	Malignant Tumor Of Sublingual Gland Malignant Tumor Of The Sublingual Gland
Papillary Adenocarcinoma	Infiltrating And Papillary Adenocarcinoma Infiltrating Papillary Adenocarcinoma Adenocarcinoma Papillary Adenocarcinoma, Papillary
Mature Teratoma	Dermoid Cyst Benign Teratoma
Breast Mucinous Carcinoma	Mucinous Carcinoma Of Breast Invasive Mucinous Breast Carcinoma
Bartholin'S Gland Carcinoma	Bartholin Gland Carcinoma Carcinoma Of Bartholin'S Gland
Esophagus Adenocarcinoma	Esophageal Adenocarcinoma Oesophageal Adenocarcinoma Adenocarcinoma Of Esophagus Adenocarcinoma Of The Esophagus
Rectal Benign Neoplasm	Neoplasm Of Rectum Rectal Tumor Rectum Neoplasm Neoplasm Of The Rectum Rectal Neoplasms Primary Rectal Cancer Rectal Ampulla Cancer Cancer Of The Rectum Carcinoma Of Rectum Primary Malignant Neoplasm Of Rectum Rectal Cancer Rectal Carcinoma
Intestinal Benign Neoplasm	Intestinal Neoplasms Intestinal Tumors Intestine Growth Neoplasm Of Intestinal Tract
Female Urethral Cancer	Female Urethral Malignant Neoplasm
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Biliary Tract Benign Neoplasm	Extrahepatic Bile Duct Neoplasm Neoplasm Of Extrahepatic Bile Ducts Tumor Of The Extrahepatic Bile Duct
Cecal Disease	Cecal Diseases Disorder Of Cecum
Adenocarcinoma In Situ
Lymphangioma	Lymphatic Malformation Lymphatic Malformations Benign Lymphangioma Congenital Lymphangioma Lymphangiomas
Keratinizing Squamous Cell Carcinoma	Squamous Cell Carcinoma, Keratinizing Keratinizing Epidermoid Carcinoma
Colon Mucinous Adenocarcinoma	Colonic Mucinous Adenocarcinoma Mucinous Adenocarcinoma Of The Colon
Anus Basaloid Carcinoma	Basaloid Carcinoma Of The Anus Anal Basaloid Carcinoma
Gallbladder Signet Ring Cell Adenocarcinoma	Signet Ring Cell Carcinoma Of The Gallbladder
Rectum Adenocarcinoma	Rectal Adenocarcinoma Adenocarcinoma Of Rectum
Colon Adenoma	Adenomatous Polyp Of Colon
Gastrointestinal System Benign Neoplasm
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Anus Disease	Anal Fissure Ulcer Of Anus Anus Diseases Anal Disease Anal Fissure And Fistula Anal Ulcer Fissure In Ano Nontraumatic Tear Of Anus Solitary Anal Ulcer Abnormality Of The Anus Anal Disorders Ulcer Of Anus And Rectum Solitary Ulcer Of Anus Stercoral Ulcer Of Anus
Anus Cancer	Anal Cancer Anal Carcinoma Malignant Anal Tumor Cancer Of The Anus Malignant Neoplasm Of Anus Anus Neoplasms
Germ Cell And Embryonal Cancer	Germ Cell And Embryonal Neoplasm
Cystic Basal Cell Carcinoma	Skin Cystic Basal Cell Carcinoma
Germ Cell Cancer	Malignant Germ Cell Tumor Neoplasms, Germ Cell And Embryonal Germ Cell Neoplasm Germ Cell Tumour Malignant Tumor Of The Germ Cell Neoplasms Germ Cell Malignant Germ Cell Neoplasm
Rectal Disease	Rectal Diseases Rectal Disorders
Gastric Hemangioma	Hemangioma Of Stomach
Ovary Adenocarcinoma	Ovarian Adenocarcinoma Adenocarcinoma Of The Ovary Ovarian Adenoacanthoma Adenocarcinoma Of Ovary
Clear Cell Basal Cell Carcinoma	Skin Clear Cell Basal Cell Carcinoma
Lynch Syndrome	Hereditary Nonpolyposis Colon Cancer Hereditary Nonpolyposis Colorectal Cancer Hereditary Nonpolyposis Colorectal Carcinoma Hereditary Nonpolyposis Colorectal Neoplasms Familial Nonpolyposis Colon Cancer Hnpcc Coca 1 Hereditary Defective Mismatch Repair Syndrome Hereditary Non-Polyposis Colon Cancer Hereditary Non-Polyposis Colon Cancer Syndrome Hereditary Non-Polyposis Colorectal Cancer Hereditary Non-Polyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colon Cancer Syndrome Hereditary Nonpolyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colorectal Neoplasm Hnpcc - Hereditary Nonpolyposis Colon Cancer Cancer Family Syndrome Familial Nonpolyposis Colorectal Cancer Colon Cancer, Familial Nonpolyposis Colorectal Neoplasms, Hereditary Nonpolyposis Cancer, Colorectal, Nonpolyposis, Hereditary Colorectal Cancer, Hereditary Nonpolyposis, Type 1
Epididymis Adenocarcinoma	Adenocarcinoma Of The Epididymis
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Epididymis Cancer	Malignant Tumor Of Epididymis Malignant Epididymal Tumor Malignant Neoplasm Of Epididymis Neoplasm Of Epididymis
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P1727	Super-TDU	Antagonist	99.18%	Unkown
HY-P1727A	Super-TDU TFA	Antagonist	/	Unkown
HY-RS02430	CDX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18606	Cdx2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25092	Cdx2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CDX2	VGNC	VGNC:106254
Bos taurus	CDX2	VGNC	VGNC:106684
Mus musculus	CDX2	MGD	MGI:88361
Felis catus	CDX2	VGNC	VGNC:60723
Rattus norvegicus	CDX2	RGD	RGD:621234
Canis familiaris	CDX2	VGNC	VGNC:39085
Others	CDX2	NCBI