SAMD3 - sterile alpha motif domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 154075

About SAMD3

This gene has 15 transcripts (splice variants), 121 orthologues and 4 paralogues. Broad expression in lymph node (RPKM 2.9), spleen (RPKM 2.8) and 22 other tissues.

SAMD3 Products (3)

mRNA Protein Name
NM_001017373.4 NP_001017373.2 sterile alpha motif domain-containing protein 3 isoform 1
NM_001258275.3 NP_001245204.1 sterile alpha motif domain-containing protein 3 isoform 1
NM_001277185.2 NP_001264114.1 sterile alpha motif domain-containing protein 3 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
23455924 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SAMD3 Protein Structure

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (3 - 64)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 520 a.a.
Protein Preferred Names Protein Names

sterile alpha motif domain-containing protein 3

  • SAM domain-containing protein 3

SAMD3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
SAMD3 Q8N6K7 HSPD1 Homo sapiens P10809
Y2H Array
31515488
Intra
SAMD3 Q8N6K7 KDM1A Homo sapiens O60341
Anti Tag CoIP
23455924
Intra
SAMD3 Q8N6K7 KDM1A Homo sapiens O60341
Y2H
23455924
Intra
SAMD3 Q8N6K7 LMO3 Homo sapiens Q8TAP4
Y2H Prey Pooling
25416956
Intra
SAMD3 Q8N6K7 CFAP206 Homo sapiens Q8IYR0
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma

  • DMSMFH

  • Bone Dysplasia With Medullary Fibrosarcoma

  • Bdmf

  • Bone Dysplasia With Malignant Fibrous Histiocytoma

  • Hardcastle Syndrome

  • Diaphyseal Medullary Stenosis-Bone Malignancy Syndrome

  • Myopathy, Limb-Girdle, With Bone Fragility

  • Bone Dysplasia-Medullary Fibrosarcoma Syndrome

  • Diaphyseal Medullary Stenosis-Malignant Fibrous Histiocytoma Syndrome

  • Dms-Mfh

  • Limb-Girdle Myopathy With Bone Fragility

  • Stenosis, Medullary, Diaphyseal, With Malignant Fibrous Histiocytoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS12425 SAMD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SAMD3 VGNC VGNC:45851
Rattus norvegicus SAMD3 RGD RGD:1587834
Felis catus SAMD3 VGNC VGNC:64862
Bos taurus SAMD3 VGNC VGNC:34271
Macaca mulatta SAMD3 VGNC VGNC:77079
Mus musculus SAMD3 MGD MGI:2685469
Others SAMD3 NCBI