77500-30-2
77500-30-2
Chemical Structure
PTP1B-IN-33
- CAS No.: 77500-30-2
- Formula:C18H14N2O3
- Molecular Weight:306.32
InChIKey: YAXOQPFSIOTBRL-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(O1)C(NC2=CC=CC=C2)=O)NC3=CC=CC=C3
Biological Activity: PTP1B-IN-33 is a PTP1B inhibitor with a human IC50 of 2.45 μM and over 20-fold selectivity for PTP1B over SHP2. PTP1B-IN-33 enhances π-Alkyl interaction with PTP1B to increase WPD loop closure degree. PTP1B-IN-33 can be used for the research of cancer, diabetes, autoimmune deficiency diseases[1].
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PTP1B-IN-33 | PTP1B-IN-33 is a PTP1B inhibitor with a human IC50 of 2.45 μM and over 20-fold selectivity for PTP1B over SHP2. PTP1B-IN-33 enhances π-Alkyl interaction with PTP1B to increase WPD loop closure degree. PTP1B-IN-33 can be used for the research of cancer, diabetes, autoimmune deficiency diseases. | |||||||||||||||||||||
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References
Keywords
