Mylk3 - myosin light chain kinase 3 Gene

Also Known as MLCK; RGD1305801

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291926

Summary

Enables calmodulin-dependent protein kinase activity and Myosin light chain kinase activity. Involved in myofibril assembly; positive regulation of sarcomere organization; and protein phosphorylation. Located in cytosol. Orthologous to human MYLK3 (Myosin light chain kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Mylk3 Products (1)

mRNA Protein Name
NM_001110810.1 NP_001104280.1 myosin light chain kinase 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: Inferred from direct assay
17885681 RGD
enables myosin light chain kinase activity IMP
IMP: Inferred from mutant phenotype
18202317 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in cardiac myofibril assembly IMP
IMP: Inferred from mutant phenotype
17885681 RGD
involved in positive regulation of sarcomere organization IDA
IDA: Inferred from direct assay
17885681 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
17885681 RGD
involved in sarcomere organization IMP
IMP: Inferred from mutant phenotype
18202317 RGD
involved in sarcomerogenesis IMP
IMP: Inferred from mutant phenotype
17885681 RGD
Cellular Component GO Annotation Evidence Referencias Source
located in cytosol IDA
IDA: Inferred from direct assay
17885681 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin light chain kinase 3

  • cardiac-MLCK

  • cardiac-MyBP-C-associated Ca/CaM kinase

  • putative myosin light chain kinase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS08925 MYLK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22661 Mylk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29175 Mylk3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mylk3 NCBI NCBI:91807