Ppib - peptidylprolyl isomerase B Gene

Also Known as Cphn2; Cphn-2; CyP-20b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19035

Summary

Predicted to enable RNA polymerase binding activity; cyclosporin A binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation by host of viral genome replication; and protein stabilization. Part of endoplasmic reticulum chaperone complex. Is expressed in several structures, including axial skeleton; cranium; otic capsule; and pancreas tip epithelium. Used to study osteogenesis imperfecta type 9. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B). [provided by Alliance of Genome Resources, Apr 2022]

Ppib Products (1)

mRNA Protein Name
NM_011149.2 NP_035279.2 peptidyl-prolyl cis-trans isomerase B precursor
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
27119146 MGI
Cellular Component GO Annotation Evidence Références Source
part of endoplasmic reticulum chaperone complex IDA
IDA: Inferred from direct assay
12475965 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase B

  • CYP-S1

  • PPIase B

  • S-cyclophilin

  • SCYLP

  • cyclophilin B

  • rotamase B

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppib NCBI NCBI:5479