477-83-8
477-83-8
Chemical Structure
Damnacanthol
- No. CAS: 477-83-8
- Formula:C16H12O5
- Molecular Weight:284.26
IUPAC Name: 3-hydroxy-2-(hydroxymethyl)-1-methoxyanthracene-9,10-dione
InChIKey: ASFZQCLAQPBWDN-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(CO)C(OC)=C13)=O
Biological Activity: Damnacanthol is a natural product that can be isolated from Damnacanthus major[1]. Damnacanthol has anti-15-lipoxygenase activity and can inhibit nitric oxide production in LPS-activated macrophages RAW 264.7 cells[2].
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Damnacanthol | 99.86% | Damnacanthol is a natural product that can be isolated from Damnacanthus major. Damnacanthol has anti-15-lipoxygenase activity and can inhibit nitric oxide production in LPS-activated macrophages RAW 264.7 cells. | ||||||||||||||||||||
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References
- [1]. Ayyangar N R, et al. Anthraquinone and anthrone series—XXIII: The non-identity of 1: 3: 8-trihydroxy-2-hydroxymethyl-anthraquinone with versicolorin and a synthesis of damnacanthol and damnacanthal. Tetrahedron, 1959, 6(4): 331-337.
- [2]. Dzoyem JP, et al. Inhibition of Nitric Oxide Production in LPS-Stimulated RAW 264.7 Macrophages and 15-LOX Activity by Anthraquinones from Pentas schimperi. Planta Med. 2016 Sep;82(14):1246-51. [Content Brief]
Keywords
