2. Metabolic Enzyme/Protease Immunology/Inflammation
  3. Lipoxygenase NO Synthase
  4. Damnacanthol

Damnacanthol is a natural product that can be isolated from Damnacanthus major. Damnacanthol has anti-15-lipoxygenase activity and can inhibit nitric oxide production in LPS-activated macrophages RAW 264.7 cells.

For research use only. We do not sell to patients.

Damnacanthol Chemical Structure

Damnacanthol Chemical Structure

CAS No. : 477-83-8

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Based on 1 publication(s) in Google Scholar

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Description

Damnacanthol is a natural product that can be isolated from Damnacanthus major[1]. Damnacanthol has anti-15-lipoxygenase activity and can inhibit nitric oxide production in LPS-activated macrophages RAW 264.7 cells[2].

IC50 & Target[2]

15-LOX

 

Molecular Weight

284.26

Formula

C16H12O5
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(CO)C(OC)=C13)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Damnacanthol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Damnacanthol477-83-8LipoxygenaseNO SynthaseLOXNitric oxide synthasesNOSInhibitorinhibitorinhibit

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