Fgg - fibrinogen gamma chain Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24367

Summary

Enables identical protein binding activity. Involved in cellular response to cytokine stimulus; negative regulation of platelet aggregation; and platelet maturation. Located in blood microparticle and cytoplasm. Biomarker of obesity; pancreatitis; and pulmonary embolism. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; and multiple myeloma. Orthologous to human FGG (fibrinogen gamma chain). [provided by Alliance of Genome Resources, Apr 2022]

Fgg Products (1)

mRNA Protein Name
NM_012559.2 NP_036691.2 fibrinogen gamma chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
21448983 RGD
Biological Process GO Annotation Evidence Referencias Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
11071643 RGD
involved in cellular response to interleukin-6 IEP
IEP: Inferred from expression pattern
11071643 RGD
involved in platelet maturation IEP
IEP: Inferred from expression pattern
1991167 RGD
Cellular Component GO Annotation Evidence Referencias Source
located in blood microparticle IDA
IDA: Inferred from direct assay
22014850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibrinogen gamma chain

  • fibrinogen, gamma polypeptide

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS04925 FGG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17794 Fgg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24262 Fgg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgg NCBI NCBI:2266
Mus musculus Fgg NCBI NCBI:99571