Cd300lf - CD300 molecule like family member F Gene
Also Known as CLM1; CLIM1; CLM-1; Digr2; IREM1; LMIR3; Pigr3; IgSF13; F730004D16Rik
Species: Mus musculus
Summary
Enables several functions, including interleukin-4 receptor binding activity; phosphatidylserine binding activity; and virus receptor activity. Involved in several processes, including interleukin-13-mediated signaling pathway; positive regulation of interleukin-4-mediated signaling pathway; and regulation of apoptotic cell clearance. Acts upstream of or within osteoclast differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in retina. Orthologous to human CD300LF (CD300 molecule like family member f). [provided by Alliance of Genome Resources, Apr 2022]
Cd300lf Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001169153.1 | NP_001162624.1 | CMRF35-like molecule 1 isoform 1 precursor |
| NM_001347648.1 | NP_001334577.1 | CMRF35-like molecule 1 isoform 3 precursor |
| NM_145634.3 | NP_663609.2 | CMRF35-like molecule 1 isoform 2 precursor |
| Molecular Function GO Annotation | Evidence | Referencias | Source |
|---|---|---|---|
| enables ceramide binding |
IDA
IDA: Inferred from direct assay
|
23123064 | MGI |
| enables interleukin-4 receptor binding |
IDA
IDA: Inferred from direct assay
|
26124135 | MGI |
| enables phosphatidylserine binding |
IDA
IDA: Inferred from direct assay
|
21865548 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
14662855 | MGI |
| enables virus receptor activity |
IMP
IMP: Inferred from mutant phenotype
|
27540007 | MGI |
| Biological Process GO Annotation | Evidence | Referencias | Source |
|---|---|---|---|
| involved in interleukin-13-mediated signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
26124135 | MGI |
| involved in negative regulation of apoptotic cell clearance |
IMP
IMP: Inferred from mutant phenotype
|
26768664 | MGI |
| involved in negative regulation of mast cell activation |
IMP
IMP: Inferred from mutant phenotype
|
23123064 | MGI |
| acts upstream of or within osteoclast differentiation |
IDA
IDA: Inferred from direct assay
|
14662855 | MGI |
| involved in positive regulation of apoptotic cell clearance |
IDA
IDA: Inferred from direct assay
|
21865548 | MGI |
| involved in positive regulation of apoptotic cell clearance |
IMP
IMP: Inferred from mutant phenotype
|
26768664 | MGI |
| involved in positive regulation of interleukin-4-mediated signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
26124135 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
CMRF35-like molecule 1 |
|
|
Recombinant Cd300lf Proteins
| Referencia número | Nombre del producto | Accession | Pureza |
|---|---|---|---|
| HY-P76793 | CD300LF Protein, Mouse (HEK293, Fc) | Q6SJQ7 (E20-S193) | ≥ 90%, as determined by reducing SDS-PAGE. |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Homo sapiens | Cd300lf | NCBI | NCBI:146722 |
| Rattus norvegicus | Cd300lf | NCBI | NCBI:287818 |