2. Gene
  3. CD300LF - CD300 molecule like family member f Gene

CD300LF - CD300 molecule like family member f Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CLM1; NKIR; CLM-1; IREM1; LMIR3; CD300f; IREM-1; IgSF13

Gene ID: 146722 | Gene type: protein coding

About CD300LF

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,694,317-74,712,923 (from NCBI)

This gene has 10 transcripts (splice variants), 288 orthologues and 13 paralogues. Biased expression in spleen (RPKM 9.3), bone marrow (RPKM 8.2) and 10 other tissues.

Summary

This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

CD300LF Products(7)

mRNA Protein Name
NM_001289082.2 NP_001276011.1 CMRF35-like molecule 1 isoform 2
NM_001289083.2 NP_001276012.1 CMRF35-like molecule 1 isoform 3 precursor
NM_001289084.2 NP_001276013.1 CMRF35-like molecule 1 isoform 4
NM_001289085.2 NP_001276014.1 CMRF35-like molecule 1 isoform 5
NM_001289086.2 NP_001276015.1 CMRF35-like molecule 1 isoform 6
NM_001289087.2 NP_001276016.1 CMRF35-like molecule 1 isoform 7 precursor
NM_139018.5 NP_620587.2 CMRF35-like molecule 1 isoform 1 precursor

CD300LF Protein Structure

V-set

V-set: Immunoglobulin V-set domain (21 - 116)

SIT

SIT: SHP2-interacting transmembrane adaptor protein, SIT (157 - 260)

  • 0
  • 100
  • 200
  • 290 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 1

CD300 antigen-like family member F

Recombinant CD300LF Proteins

Cat. No. Product Name Accession Purity
HY-P71595 CD300LF Protein, Human (His) Q8TDQ1 (20T-156S) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02231 CD300LF Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CD300LF VGNC VGNC:70910
Mus musculus CD300LF MGD MGI:2442359
Rattus norvegicus CD300LF RGD RGD:1309733
Felis catus CD300LF VGNC VGNC:60611
Others CD300LF NCBI