CD300LB - CD300 molecule like family member b Gene

Also Known as CLM7; CLM-7; IREM3; TREM5; CD300b; IREM-3; TREM-5; CMRF35-A2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 124599

About CD300LB

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,521,174-74,531,475 (from NCBI)

This gene has 2 transcripts (splice variants), 73 orthologues and 13 paralogues. Biased expression in appendix (RPKM 4.4), bone marrow (RPKM 2.5) and 11 other tissues.

Summary

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]

CD300LB Products (1)

mRNA Protein Name
NM_174892.4 NP_777552.3 CMRF35-like molecule 7 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
20959446 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20959446 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD300LB Protein Structure

V-set

V-set: Immunoglobulin V-set domain (54 - 156)

  • 0
  • 100
  • 200
  • 238 a.a.
Protein Preferred Names Protein Names

CMRF35-like molecule 7

  • CD300 antigen like family member B

CD300LB Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CD300LB A8K4G0 CD300A Homo sapiens Q9UGN4
Anti Tag CoIP
29051512
Intra
CD300LB A8K4G0 CD300E Homo sapiens Q496F6
Anti Tag CoIP
20959446
Intra
CD300LB A8K4G0 CD300E Homo sapiens Q496F6
Anti Tag CoIP
29051512
Intra
CD300LB A8K4G0 CD300LF Homo sapiens Q8TDQ1
Anti Tag CoIP
20959446
Intra
CD300LB A8K4G0 ATP2B2 Homo sapiens Q01814
Anti Tag CoIP
33961781
Intra
CD300LB A8K4G0 CD300C Homo sapiens Q08708
Anti Tag CoIP
20959446
Intra
CD300LB A8K4G0 CD300LB Homo sapiens A8K4G0
Anti Tag CoIP
29051512
Intra
CD300LB A8K4G0 CD300LF Homo sapiens Q8TDQ1
Anti Tag CoIP
29051512
Intra
CD300LB A8K4G0 CD300LB Homo sapiens A8K4G0
Anti Tag CoIP
20959446
Intra
CD300LB A8K4G0 RAD51B Homo sapiens O15315
Anti Tag CoIP
33961781
Intra
CD300LB A8K4G0 CD300LD Homo sapiens Q6UXZ3
Anti Tag CoIP
22291008
Intra
CD300LB A8K4G0 CD300C Homo sapiens Q08708
Anti Tag CoIP
29051512
Intra
CD300LB A8K4G0 DDX19B Homo sapiens Q9UMR2
Anti Tag CoIP
33961781
Intra
CD300LB A8K4G0 ATP13A1 Homo sapiens Q9HD20
Anti Tag CoIP
33961781
Intra
CD300LB A8K4G0 CD300LD Homo sapiens Q6UXZ3
Anti Tag CoIP
29051512
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CD300LB Proteins

Cat. No. Product Name Accession Purity
HY-P72774 CD300LB Protein, Human (HEK293, hFc) AAH28091.1 (I55-H187) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02229 CD300LB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19539 Cd300lb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26035 Cd300lb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CD300LB VGNC VGNC:99135
Rattus norvegicus CD300LB RGD RGD:1583718
Mus musculus CD300LB MGD MGI:2685099
Others CD300LB NCBI