Arpc3 - actin related protein 2/3 complex, subunit 3 Gene

Also Known as p21-Ar; p21Arc; p21-ARC; 1110006A04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56378

About Arpc3

Chromosome 5: 122,529,941-122,552,247 forward strand.GRCm39:CM000998.3

This gene has 8 transcripts (splice variants), 219 orthologues and is associated with 11 phenotypes. Ubiquitous expression in placenta adult (RPKM 128.4), large intestine adult (RPKM 16.1) and 28 other tissues.

Summary

Predicted to be a structural constituent of Cytoskeleton. Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Located in lamellipodium. Is expressed in lower jaw tooth and tooth. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Arpc3 Products (1)

mRNA Protein Name
NM_019824.4 NP_062798.1 actin-related protein 2月3日 complex subunit 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
31146259 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in regulation of synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
34269176 MGI
involved in regulation of synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
34269176 MGI
Cellular Component GO Annotation Evidence Referencias Source
located in lamellipodium IDA
IDA: Inferred from direct assay
15294161 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Arpc3 Protein Structure

P21-Arc

P21-Arc: pfam04062 (0 - 172)

  • 0
  • 100
  • 178 a.a.
Protein Preferred Names Protein Names

actin-related protein 2/3 complex subunit 3

  • Arp2/3 complex subunit p21-Arc

  • arp2/3 complex 21 kDa subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS01018 ARPC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01019 Arpc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01020 Arpc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arpc3 NCBI NCBI:10094