UBR3 - ubiquitin protein ligase E3 component n-recognin 3 Gene

Also Known as ZNF650

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130507

About UBR3

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:169,827,454-170,084,131 (from NCBI)

This gene has 10 transcripts (splice variants), 215 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 13.7), thyroid (RPKM 11.5) and 25 other tissues.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; sensory perception of smell; and suckling behavior. Predicted to act upstream of or within in utero embryonic development and olfactory behavior. Predicted to be integral component of membrane. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

UBR3 Products (1)

mRNA Protein Name
NM_172070.4 NP_742067.3 E3 ubiquitin-protein ligase UBR3

UBR3 Protein Structure

zf-UBR

zf-UBR: Putative zinc finger in N-recognin (UBR box) (119 - 188)

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  • 1888 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase UBR3

  • N-recognin-3

UBR3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810024 Ubr3 Antibody (YA9368) WB, IP, ELISA human, mouse, rat

Related Diseases

Diseases Alias
Johanson-Blizzard Syndrome

  • JBS

  • Nasal Alar Hypoplasia, Hypothyroidism, Pancreatic Achylia, And Congenital Deafness

  • Nasal Alar Hypoplasia, Hypothyroidism, Pancreatic Achylia And Congenital Deafness

  • Johanson Blizzard Syndrome
Myh-9 Related Disease

  • Myh9-Related Disease

  • Myh9-Rd

  • Myh9-Related Disorder

  • Myh9-Related Syndrome

  • Myh9-Related Syndromic Thrombocytopenia

  • Sebastian Syndrome
Usher Syndrome, Type I

  • USH1

  • Usher Syndrome Type 1

  • Us1

  • Usher Syndrome, Type 1b

  • Usher Syndrome Type 1e

  • Retinitis Pigmentosa And Congenital Deafness

  • Usher Syndrome, Type Ie

  • USH1E

  • Usher Syndrome, Type 1e

  • Usher Syndrome, Type 1a

  • Usher Syndrome, Type Ib

  • Usher Syndrome Type 1b

  • Usher Syndrome Type Ie

  • Usher Syndrome Type I

  • Usher 1

  • Usher Syndrome, Type 1

  • Ush1a

  • Usher Syndrome, Type I, French Variety

  • Usher Syndrome, Type Ia

  • Usher Syndrome 1b

  • USH1B

  • Usher'S Syndrome Type 1b

  • Usher Syndrome Type Ib

  • Ushib
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15388 UBR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus UBR3 RGD RGD:1565257
Felis catus UBR3 VGNC VGNC:66786
Mus musculus UBR3 MGD MGI:1861100
Macaca mulatta UBR3 VGNC VGNC:99419
Canis familiaris UBR3 VGNC VGNC:53111
Bos taurus UBR3 VGNC VGNC:55173
Others UBR3 NCBI