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KRTCAP3 - keratinocyte associated protein 3 Gene

Also Known as KCP3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 200634

About KRTCAP3

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,442,381-27,446,481 (from NCBI)

This gene has 7 transcripts (splice variants), 180 orthologues and 1 paralogue. Broad expression in colon (RPKM 15.6), small intestine (RPKM 13.3) and 22 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

KRTCAP3 Products (3)

mRNA	Protein	Name
NM_001168364.2	NP_001161836.1	keratinocyte-associated protein 3
NM_001321325.2	NP_001308254.1	keratinocyte-associated protein 3
NM_173853.4	NP_776252.2	keratinocyte-associated protein 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRTCAP3 Protein Structure

BCLP

0
100
200
240 a.a.

Protein Preferred Names	Protein Names
keratinocyte-associated protein 3	keratinocytes associated protein 3

KRTCAP3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	KRTCAP3	Q53RY4	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	KRTCAP3	Q53RY4	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	KRTCAP3	Q53RY4	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	KRTCAP3	Q53RY4	MEOX2	Homo sapiens	Q6FHY5	Validated Y2H	32296183
Intra	KRTCAP3	Q53RY4	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	KRTCAP3	Q53RY4	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Short-Rib Thoracic Dysplasia 10 With Or Without Polydactyly	SRTD10 Short-Rib Thoracic Dysplasia 10 Without Polydactyly Short Rib-Polydactyly Syndrome
Retinitis Pigmentosa 71	RP71 Retinitis Pigmentosa, Type 71
Bardet-Biedl Syndrome 22	BBS22 Bardet-Biedl Syndrome 20, Formerly Bbs20, Formerly
Cone-Rod Dystrophy 2	Cone-Rod Dystrophy CORD2 Cone-Rod Retinal Dystrophy Rcrd2 Cone-Rod Retinal Dystrophy 2 Crd2 Cord Crd Retinal Cone-Rod Dystrophy Cone-Rod Retinal Dystrophy-2 Retinal Cone-Rod Dystrophy 2 Tapetoretinal Degeneration Cone-Rod Degeneration Cone Rod Dystrophy Dystrophy, Cone-Rod Dystrophy, Cone-Rod, Type 2 Retinitis Pigmentosa Retinitis Pigmentosa 2 Progressive Cone-Rod Dystrophy
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07473	KRTCAP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KRTCAP3	RGD	RGD:1596516
Macaca mulatta	KRTCAP3	VGNC	VGNC:74152
Canis familiaris	KRTCAP3	VGNC	VGNC:42545
Bos taurus	KRTCAP3	VGNC	VGNC:30752
Mus musculus	KRTCAP3	MGD	MGI:1917065
Felis catus	KRTCAP3	VGNC	VGNC:63176