SRSF4 - serine and arginine rich splicing factor 4 Gene

Homo sapiens

Also known as SFRS4; SRP75

Gene ID: 6429 | Gene type: protein coding

About SRSF4

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:29,147,743-29,181,900 (from NCBI)

This gene has 8 transcripts (splice variants), 239 orthologues and 8 paralogues. Ubiquitous expression in placenta (RPKM 33.0), bone marrow (RPKM 32.4) and 25 other tissues.

Summary

This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009]

SRSF4 Products(1)

mRNA	Protein	Name
NM_005626.5	NP_005617.2	serine/arginine-rich splicing factor 4

SRSF4 Protein Structure

RRM_1

0
100
200
300
400
494 a.a.

Protein Preferred Names

Protein Names

serine/arginine-rich splicing factor 4

SR splicing factor 4

Related Diseases

Diseases

Alias

Frontotemporal Dementia

Pallidopontonigral Degeneration	Frontotemporal Lobar Degeneration
Semantic Dementia	FTD
Frontotemporal Lobe Dementia	Multiple System Tauopathy With Presenile Dementia
Dementia, Frontotemporal	Frontotemporal Dementia With Parkinsonism
Mstd	Frontotemporal Lobar Degeneration With Tau Inclusions
Ftld With Tau Inclusions	Dementia, Frontotemporal, With Parkinsonism
Fldem	Ftdp17
Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex	Ddpac
Wilhelmsen-Lynch Disease	Wld
Ppnd	Dementia, Frontotemporal, With Or Without Parkinsonism
Semantic Primary Progressive Aphasia	Semantic Variant Ppa
Wilhemsen-Lynch Disease	Frontotemporal Dementia-Amyotrophic Lateral Sclerosis
Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17	Ftd-Als
Ftld	Pick Complex
Pick Disease Of The Brain	Frontotemporal Dementia With Parkinsonism-17
Grn-Related Frontotemporal Dementia	Frontotemporal Dementia With Motor Neuron Disease
Dementia In Fronto-Temporal Lobar Degeneration	Ftd - [Frontotemporal Dementia]
Temple Dementia	Frontal Lobe Dementia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13795	SRSF4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SRSF4	VGNC	VGNC:46820
Mus musculus	SRSF4	MGD	MGI:1890577
Bos taurus	SRSF4	VGNC	VGNC:35302
Rattus norvegicus	SRSF4	RGD	RGD:1561347
Macaca mulatta	SRSF4	VGNC	VGNC:100150
Felis catus	SRSF4	VGNC	VGNC:65696

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