2448341-58-8
2448341-58-8
Chemical Structure
NV03
- CAS No.: 2448341-58-8
- Formula:C19H27N5O2S
- Molecular Weight:389.51
IUPAC Name: N-(3-(diethylamino)propyl)-2-(5,9-dimethyl-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)acetamide
InChIKey: KNZQAVKYBBYDKV-UHFFFAOYSA-N
SMILES: O=C1N(CC(NCCCN(CC)CC)=O)N=C(C)N2C1=C(C)C3=C2C=CS3
Biological Activity: NV03 is a potent and selective antagonist of Ubiquitin-like with PHD and RING finger domains 1 (UHRF1)-H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a Kd of 2.4 μM. NV03 is also a ligand for E3 ligase. NV03 can be studied in anticancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NV03 | 99.77% | NV03 is a potent and selective antagonist of Ubiquitin-like with PHD and RING finger domains 1 (UHRF1)-H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a Kd of 2.4 μM. NV03 is also a ligand for E3 ligase. NV03 can be studied in anticancer research. | ||||||||||||||||||||
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References
Keywords
