148-79-8
148-79-8
Chemical Structure
Thiabendazole
Synonym(s): Tiabendazole; 2-(4-Thiazolyl)benzimidazole
- CAS No.: 148-79-8
- Formula:C10H7N3S
- Molecular Weight:201.25
IUPAC Name: 4-(1H-benzo[d]imidazol-2-yl)thiazole
InChIKey: WJCNZQLZVWNLKY-UHFFFAOYSA-N
SMILES: C1(C2=CSC=N2)=NC3=CC=CC=C3N1
Biological Activity: Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thiabendazole | 99.94% | Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling. | ||||||||||||||||||||
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Thiabendazole (Standard) | 99.96% | Thiabendazole (Standard) is the analytical standard of Thiabendazole. This product is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties. | ||||||||||||||||||||
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Thiabendazole-13C6 | 99.8% | Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property. | ||||||||||||||||||||
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Thiabendazole-d6 | Thiabendazole-d6 is a deuterated labeled Thiabendazole (HY-B0263). Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling. | |||||||||||||||||||||
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Thiabendazole-d4 | 98.84% | Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent. | ||||||||||||||||||||
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References
- [1]. Budetić M, et al. Review of Characteristics and Analytical Methods for Determination of Thiabendazole. Molecules. 2023 May 6;28(9):3926. [Content Brief]
- [2]. Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8. [Content Brief]
- [3]. Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379. [Content Brief]
- [4]. Park J, et al. Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish. Environ Int. 2023 Jun;176:107973. [Content Brief]
- [5]. Elgebaly SA, et al. Thiabendazole-induced suppression of renal damage in a murine model of autoimmune disease. Am J Pathol. 1984 May;115(2):204-11. [Content Brief]
