CNGA2 - Cnga2 cyclic nucleotide gated channel subunit alpha 2 Gene

Also Known as Cncg4; OLFCH

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25411

Summary

Enables cGMP binding activity; identical protein binding activity; and intracellular cyclic nucleotide activated cation channel activity. Involved in membrane depolarization and sensory perception of smell. Located in perikaryon and plasma membrane. Part of intracellular cyclic nucleotide activated cation channel complex. Orthologous to human CNGA2 (cyclic nucleotide gated channel subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

CNGA2 Products (1)

mRNA Protein Name
NM_012928.2 NP_037060.2 cyclic nucleotide-gated olfactory channel

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cGMP binding IDA
IDA: Inferred from direct assay
18048449 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
22786723 RGD
enables intracellularly cAMP-activated cation channel activity IDA
IDA: Inferred from direct assay
1697649 RGD
enables intracellularly cGMP-activated cation channel activity IDA
IDA: Inferred from direct assay
1697649 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
22786723 RGD
Biological Process GO Annotation Evidence References Source
involved in calcium ion transport IDA
IDA: Inferred from direct assay
9878057 RGD
involved in membrane depolarization IDA
IDA: Inferred from direct assay
1697649 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
10377344 RGD
involved in sodium ion transport IDA
IDA: Inferred from direct assay
10377344 RGD
Cellular Component GO Annotation Evidence References Source
part of intracellular cyclic nucleotide activated cation channel complex IDA
IDA: Inferred from direct assay
22786723 RGD
located in non-motile cilium membrane IDA
IDA: Inferred from direct assay
10377344 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
12021210 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic nucleotide-gated olfactory channel

  • CNG channel alpha-2

  • CNG-2

  • CNG2

  • cyclic nucleotide gated channel 4

  • cyclic nucleotide gated channel alpha 2

  • cyclic nucleotide-gated cation channel 2

  • cyclic nucleotide-gated olfactory channel subunit OCNC1

  • cyclic nucleotide-gated olfactory channel-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116540 L 858051 Activator / Unkown
HY-116540A L 858051 dihydrochloride Activator / Unkown
HY-RS02880 CNGA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175080 8-DY547-cGMP / Unkown
HY-RS22448 Cnga2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CNGA2 NCBI NCBI:1260