102638-08-4
Chemical Structure
Budesonide 21-palmitate
- CAS No.: 102638-08-4
- Formula:C41H64O7
- Molecular Weight:668.94
InChIKey: KZHFZMFWUHTKDG-QFDZWVBESA-N
SMILES: CCCCCCCCCCCCCCCC(OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(O2)CCC)C)=O)=O
Biological Activity: Budesonide 21-palmitate is a lipophilic ester prodrug of Budesonide (HY-13580), can be formulated into liposomal formulations. Budesonide 21-palmitate exhibts anti-inflammatory and anti-allergic activities. Budesonide 21-palmitate can achieve selective passive targeted delivery of drugs to tumor tissues (such as lung tumors). Budesonide 21-palmitate can be used for drug delivery in inflammatory and allergic research[1][2][3].
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Budesonide 21-palmitate | Budesonide 21-palmitate is a lipophilic ester prodrug of Budesonide (HY-13580), can be formulated into liposomal formulations. Budesonide 21-palmitate exhibts anti-inflammatory and anti-allergic activities. Budesonide 21-palmitate can achieve selective passive targeted delivery of drugs to tumor tissues (such as lung tumors). Budesonide 21-palmitate can be used for drug delivery in inflammatory and allergic research. | |||||||||||||||||||||
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- [1]. Tunek A, et al. Reversible formation of fatty acid esters of budesonide, an antiasthma glucocorticoid, in human lung and liver microsomes. Drug Metab Dispos. 1997 Nov;25(11):1311-7. [Content Brief]
- [2]. Manikanta Sai Ganapa, et al. Novel Oral Drug Delivery Systems for Steroids: Overview and Recent Updates. Indian Journal of Pharmaceutical Education and Research. Jul-Sep, 2020. 54(3):541-549
- [3]. Derendorf H, et al. Evaluation of pulmonary absorption using pharmacokinetic methods. J Aerosol Med. 2001;14 Suppl 1:S9-17. [Content Brief]
Keywords
