2434850-07-2
2434850-07-2
Chemical Structure
KTX-582 intermediate-2
- CAS No.: 2434850-07-2
- Formula:C21H27BrN4O5
- Molecular Weight:495.37
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-(((1r,3r)-3-(3-(methylamino)propoxy)cyclobutyl)amino)isoindoline-1,3-dione hydrobromide
InChIKey: WKWPBSOJTWLCJA-ZTBFNCIMSA-N
SMILES: O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H]4C[C@@H](C4)OCCCNC)=C3C1=O.Br
Biological Activity: KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
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KTX-582 intermediate-2 | KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. | |||||||||||||||||||||
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Keywords
