1537900-10-9
1537900-10-9
Chemical Structure
BW-AQ-113
- CAS 番号: 1537900-10-9
- Formula:C20H18ClNO5
- Molecular Weight:387.81
InChIKey: XJEWVCSTXGINMO-UHFFFAOYSA-N
SMILES: ClCC(NC1=CC(OCC)=C(C(C2=C3C=CC=C2OCC)=O)C(C3=O)=C1)=O
Biological Activity: BW-AQ-113 is an Anthraquinone (HY-N0354) derivative. BW-AQ-113 can specifically degrade MDM2 and activate the p53 pathway. BW-AQ-113 can induce apoptosis by downregulating anti-apoptotic gene Bcl-2 and regulating pro-apoptotic gene Bax and CASP3. BW-AQ-113 can be used for research of p53 wild-type hematological malignancies[1].
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BW-AQ-113 | BW-AQ-113 is an Anthraquinone (HY-N0354) derivative. BW-AQ-113 can specifically degrade MDM2 and activate the p53 pathway. BW-AQ-113 can induce apoptosis by downregulating anti-apoptotic gene Bcl-2 and regulating pro-apoptotic gene Bax and CASP3. BW-AQ-113 can be used for research of p53 wild-type hematological malignancies. | |||||||||||||||||||||
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References
Keywords
