2973401-72-6
2973401-72-6
Chemical Structure
DHX9-IN-21
- CAS 番号: 2973401-72-6
- Formula:C20H20ClN5O4S2
- Molecular Weight:493.99
InChIKey: TYJKRVLDDGWLBS-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=NC=C(C=N2)OC3CNC3)=C(C)S1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4
Biological Activity: DHX9-IN-21 (Compound 636) is a DHX9 inhibitor with an IC50 of 12.2 nM; its EC50 at the cellular level is 0.3 μM. DHX9-IN-21 exhibits antiproliferative activity against LS411N (CRC-MSI-H), with an IC50 value of 1.21 μM. DHX9-IN-21 can be used for the research of microsatellite unstable colorectal cancer[1].
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DHX9-IN-21 | DHX9-IN-21 (Compound 636) is a DHX9 inhibitor with an IC50 of 12.2 nM; its EC50 at the cellular level is 0.3 μM. DHX9-IN-21 exhibits antiproliferative activity against LS411N (CRC-MSI-H), with an IC50 value of 1.21 μM. DHX9-IN-21 can be used for the research of microsatellite unstable colorectal cancer. | |||||||||||||||||||||
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References
Keywords
