486-12-4
486-12-4
Chemical Structure
Triprolidine
- CAS 番号: 486-12-4
- Formula:C19H22N2
- Molecular Weight:278.39
IUPAC Name: (E)-2-(3-(pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine
InChIKey: CBEQULMOCCWAQT-WOJGMQOQSA-N
SMILES: CC1=CC=C(/C(C2=NC=CC=C2)=C\CN3CCCC3)C=C1
Biological Activity: Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis[1][2][3].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Triprolidine | 98.84% | Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis. | ||||||||||||||||||||
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References
- [1]. Szeberényi JB, et, al. Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation. Immunol Lett. 2001 Apr 2;76(3):175-82. [Content Brief]
- [2]. Tzeng JI, et, al. Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats. J Pharm Pharmacol. 2018 Dec;70(12):1654-1661. [Content Brief]
- [3]. Deal DL, Chandrasurin P, Shockcor J, Minick DJ, Findlay JW, McNulty MJ. Disposition and metabolism of triprolidine in mice. Drug Metab Dispos. 1992 Nov-Dec;20(6):920-7. [Content Brief]
Keywords
