Camk2d - calcium/calmodulin-dependent protein kinase II, delta Gene

Also Known as CaMK II; [d]-CaMKII; 2810011D23Rik; 8030469K03Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 108058

Summary

Enables protein serine/threonine kinase activity and transmembrane transporter binding activity. Involved in regulation of relaxation of cardiac muscle. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; cardiac muscle contraction; and protein phosphorylation. Located in several cellular components, including T-tubule; axon initial segment; and intercalated disc. Is expressed in several structures, including central nervous system; heart ventricle; olfactory epithelium; renal vasculature; and retina. Orthologous to human CAMK2D (calcium/Calmodulin dependent protein kinase II delta). [provided by Alliance of Genome Resources, Apr 2022]

Camk2d Products (9)

mRNA Protein Name
NM_001025438.2 NP_001020609.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2
NM_001025439.2 NP_001020610.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1
NM_001293663.1 NP_001280592.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 4
NM_001293664.1 NP_001280593.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 5
NM_001293665.1 NP_001280594.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 6
NM_001293666.1 NP_001280595.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 7
NM_001346635.1 NP_001333564.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 8
NM_001346636.1 NP_001333565.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 9
NM_023813.4 NP_076302.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: Inferred from direct assay
11972023 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18588881 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
20877009 MGI
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
12660151 MGI
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
12676814 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
12660151 MGI
acts upstream of or within calcium ion transport IDA
IDA: Inferred from direct assay
15652482 MGI
acts upstream of or within calcium ion transport IMP
IMP: Inferred from mutant phenotype
12660151 MGI
acts upstream of or within cardiac muscle contraction IDA
IDA: Inferred from direct assay
15652482 MGI
acts upstream of or within peptidyl-serine phosphorylation IDA
IDA: Inferred from direct assay
20877009 MGI
acts upstream of or within protein autophosphorylation IMP
IMP: Inferred from mutant phenotype
12660151 MGI
involved in regulation of relaxation of cardiac muscle IGI
IGI: Inferred from genetic interaction
23283722 MGI
acts upstream of or within regulation of sodium ion transport IDA
IDA: Inferred from direct assay
20877009 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in T-tubule IDA
IDA: Inferred from direct assay
15652482 MGI
located in axon initial segment IDA
IDA: Inferred from direct assay
20877009 MGI
is active in cochlear hair cell ribbon synapse IDA
IDA: Inferred from direct assay
29046633 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
15652482 MGI
located in intercalated disc IDA
IDA: Inferred from direct assay
20877009 MGI
located in neuromuscular junction IDA
IDA: Inferred from direct assay
17873280 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
20877009 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15652482 MGI
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
29046633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium/calmodulin-dependent protein kinase type II subunit delta

  • caM kinase II subunit delta

  • caMK-II subunit delta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-124638 MNK inhibitor 9 Inhibitor 99.38% Unkown
HY-RS29514 Camk2d Mouse Pre-designed siRNA Set A / Unkown
HY-E70797 Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase / Unkown
HY-RS01858 CAMK2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Camk2d NCBI NCBI:817