Ctsh - cathepsin H Gene
生物種: Mus musculus
Summary
This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the Cathepsin H mini, heavy, and light chains. In rat and human, these three chains can associate to form the mature enzyme, which has both Aminopeptidase and endopeptidase activities. Homozygous knockout mice for this gene exhibit impaired lung surfactant processing and reduced tumorigenesis in a pancreatic Cancer model. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]
Ctsh Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001312649.1 | NP_001299578.1 | pro-cathepsin H isoform 2 |
| NM_007801.3 | NP_031827.2 | pro-cathepsin H isoform 1 preproprotein |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
pro-cathepsin H |
|
|
Recombinant Ctsh Proteins
| 製品番号 | 製品名 | アクセッション番号 | 純度 |
|---|---|---|---|
| HY-P7752 | Cathepsin H Protein, Mouse (HEK293, His) | AAA82966.1 (A21-V333) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS18235 | Ctsh Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS03336 | CTSH Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24714 | Ctsh Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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