PHF24 - PHD finger protein 24 Gene

Also Known as GINIP

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 23349

About PHF24

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:34,665,607-34,982,544 (from NCBI)

Biased expression in brain (RPKM 19.5) and testis (RPKM 9.9).

Summary

Predicted to enable metal ion binding activity. Predicted to act upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of pain; gamma-aminobutyric acid signaling pathway; and regulation of GABAergic synaptic transmission. [provided by Alliance of Genome Resources, Apr 2022]

PHF24 Products (8)

mRNA	Protein	Name
NM_001304333.3	NP_001291262.1	PHD finger protein 24 isoform 1
NM_001347982.1	NP_001334911.1	PHD finger protein 24 isoform 2
NM_001347983.2	NP_001334912.1	PHD finger protein 24 isoform 2
NM_001395369.1	NP_001382298.1	PHD finger protein 24 isoform 3
NM_001395370.1	NP_001382299.1	PHD finger protein 24 isoform 4
NM_001395371.1	NP_001382300.1	PHD finger protein 24 isoform 5
NM_001395372.1	NP_001382301.1	PHD finger protein 24 isoform 5
NM_015297.3	NP_056112.1	PHD finger protein 24 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
PHD finger protein 24

PHF24 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	PHF24	Q9UPV7	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Prey Pooling	32296183
Intra	PHF24	Q9UPV7	TRIM35	Homo sapiens	Q9UPQ4-2	Y2H Array	32296183
Intra	PHF24	Q9UPV7	ZNF552	Homo sapiens	Q9H707	Y2H Array	32296183
Intra	PHF24	Q9UPV7	ZNF552	Homo sapiens	Q9H707	Y2H Prey Pooling	32296183
Intra	PHF24	Q9UPV7	PFDN5	Homo sapiens	Q99471	Y2H Array	32296183
Intra	PHF24	Q9UPV7	PFDN5	Homo sapiens	Q99471	Y2H Prey Pooling	32296183
Intra	PHF24	Q9UPV7	THBD	Homo sapiens	P07204	Y2H Array	32296183
Intra	PHF24	Q9UPV7	THBD	Homo sapiens	P07204	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases	Alias
Developmental And Epileptic Encephalopathy 33	DEE33 Epileptic Encephalopathy, Early Infantile, 33 Eiee33 Developmental And Epileptic Encephalopathy, 33 Early Infantile Epileptic Encephalopathy 33 Encephalopathy, Epileptic, Early Infantile, Type 33
Immunodeficiency 50	Combined Immunodeficiency Due To Moesin Deficiency IMD50 Immunodeficiency 50, X-Linked Recessive Cid Due To Moesin Deficiency Msn-Related Combined Immunodeficiency X-Linked Moesin-Associated Immunodeficiency Immunodeficiency 50 X Linked Recessive
Charcot-Marie-Tooth Disease, Axonal, Type 2cc	Charcot-Marie-Tooth Disease Axonal Type 2cc CMT2CC Charcot-Marie-Tooth Neuropathy, Type 2cc Charcot-Marie-Tooth Neuropathy Type 2cc Charcot-Marie-Tooth Disease 2cc
Myiasis	Infestation By Fly Larvae Infestation By Maggots Maggot Infestation Infestation By Larvae Of Flies Infestation By Dermatobia Infestation By Estrus Ovis Infestation By Oestrus Ovis Oestriasis Oestrosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS10426	PHF24 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22725	Phf24 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS29239	Phf24 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Bos taurus	PHF24	VGNC	VGNC:32824
Macaca mulatta	PHF24	VGNC	VGNC:103843
Canis familiaris	PHF24	VGNC	VGNC:44489
Rattus norvegicus	PHF24	RGD	RGD:1559864
Felis catus	PHF24	VGNC	VGNC:102962
Mus musculus	PHF24	MGD	MGI:2140712
Others	PHF24	NCBI