PHF24 - PHD finger protein 24 Gene

Also Known as GINIP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23349

About PHF24

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:34,665,607-34,982,544 (from NCBI)

Biased expression in brain (RPKM 19.5) and testis (RPKM 9.9).

Summary

Predicted to enable metal ion binding activity. Predicted to act upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of pain; gamma-aminobutyric acid signaling pathway; and regulation of GABAergic synaptic transmission. [provided by Alliance of Genome Resources, Apr 2022]

PHF24 Products (8)

mRNA Protein Name
NM_001304333.3 NP_001291262.1 PHD finger protein 24 isoform 1
NM_001347982.1 NP_001334911.1 PHD finger protein 24 isoform 2
NM_001347983.2 NP_001334912.1 PHD finger protein 24 isoform 2
NM_001395369.1 NP_001382298.1 PHD finger protein 24 isoform 3
NM_001395370.1 NP_001382299.1 PHD finger protein 24 isoform 4
NM_001395371.1 NP_001382300.1 PHD finger protein 24 isoform 5
NM_001395372.1 NP_001382301.1 PHD finger protein 24 isoform 5
NM_015297.3 NP_056112.1 PHD finger protein 24 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PHD finger protein 24

PHF24 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PHF24 Q9UPV7 TRIM35 Homo sapiens Q9UPQ4-2
Y2H Prey Pooling
32296183
Intra
PHF24 Q9UPV7 TRIM35 Homo sapiens Q9UPQ4-2
Y2H Array
32296183
Intra
PHF24 Q9UPV7 ZNF552 Homo sapiens Q9H707
Y2H Array
32296183
Intra
PHF24 Q9UPV7 ZNF552 Homo sapiens Q9H707
Y2H Prey Pooling
32296183
Intra
PHF24 Q9UPV7 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
Intra
PHF24 Q9UPV7 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
Intra
PHF24 Q9UPV7 THBD Homo sapiens P07204
Y2H Array
32296183
Intra
PHF24 Q9UPV7 THBD Homo sapiens P07204
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Developmental And Epileptic Encephalopathy 33

  • DEE33

  • Epileptic Encephalopathy, Early Infantile, 33

  • Eiee33

  • Developmental And Epileptic Encephalopathy, 33

  • Early Infantile Epileptic Encephalopathy 33

  • Encephalopathy, Epileptic, Early Infantile, Type 33
Immunodeficiency 50

  • Combined Immunodeficiency Due To Moesin Deficiency

  • IMD50

  • Immunodeficiency 50, X-Linked Recessive

  • Cid Due To Moesin Deficiency

  • Msn-Related Combined Immunodeficiency

  • X-Linked Moesin-Associated Immunodeficiency

  • Immunodeficiency 50 X Linked Recessive
Charcot-Marie-Tooth Disease, Axonal, Type 2cc

  • Charcot-Marie-Tooth Disease Axonal Type 2cc

  • CMT2CC

  • Charcot-Marie-Tooth Neuropathy, Type 2cc

  • Charcot-Marie-Tooth Neuropathy Type 2cc

  • Charcot-Marie-Tooth Disease 2cc
Myiasis

  • Infestation By Fly Larvae

  • Infestation By Maggots

  • Maggot Infestation

  • Infestation By Larvae Of Flies

  • Infestation By Dermatobia

  • Infestation By Estrus Ovis

  • Infestation By Oestrus Ovis

  • Oestriasis

  • Oestrosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10426 PHF24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22725 Phf24 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29239 Phf24 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PHF24 VGNC VGNC:32824
Macaca mulatta PHF24 VGNC VGNC:103843
Canis familiaris PHF24 VGNC VGNC:44489
Rattus norvegicus PHF24 RGD RGD:1559864
Felis catus PHF24 VGNC VGNC:102962
Mus musculus PHF24 MGD MGI:2140712
Others PHF24 NCBI