Cdk5rap2 - CDK5 regulatory subunit associated protein 2 Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 286919

Summary

Predicted to enable several functions, including Calmodulin binding activity; protein kinase binding activity; and tubulin binding activity. Involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and perinuclear region of cytoplasm. Predicted to be part of gamma-tubulin large complex. Human ortholog(s) of this gene implicated in Seckel syndrome; microcephaly; and primary autosomal recessive microcephaly 3. Orthologous to human CDK5RAP2 (CDK5 regulatory subunit associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Cdk5rap2 Products (1)

mRNA Protein Name
NM_173134.2 NP_775157.2 CDK5 regulatory subunit-associated protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
10721722 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
10721722 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CDK5 regulatory subunit-associated protein 2

  • CDK5 activator-binding protein C48

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02390 CDK5RAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Cdk5rap2 NCBI NCBI:55755