Otp - orthopedia homeobox Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and neuron differentiation. Predicted to act upstream of or within forebrain development and positive regulation of neuroblast proliferation. Predicted to be located in fibrillar center and nuclear body. Orthologous to human OTP (orthopedia homeobox). [provided by Alliance of Genome Resources, Apr 2022]