OTP - orthopedia homeobox Gene

Homo sapiens

Gene ID: 23440 | Gene type: protein coding

About OTP

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:77,628,712-77,638,713 (from NCBI)

This gene has 2 transcripts (splice variants), 247 orthologues and 50 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development. [provided by RefSeq, Jul 2008]

OTP Products(1)

mRNA	Protein	Name
NM_032109.3	NP_115485.1	homeobox protein orthopedia

OTP Protein Structure

Homeobox

OAR

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

homeobox protein orthopedia

orthopedia homolog

Related Diseases

Diseases

Alias

Axenfeld-Rieger Syndrome, Type 3

Axenfeld-Rieger Syndrome Type 3	RIEG3
Anterior Chamber Cleavage Syndrome	Anterior Segment Mesenchymal Dysgenesis
Axenfeld-Rieger Anomaly With Cardiac Defects And/Or Sensorineural Hearing Loss	Axenfeld-Rieger Anomaly With Or Without Cardiac Defects And/Or Sensorineural Hearing Loss
Rieger Syndrome Type 3	Axenfeld-Rieger Anomaly
Rieger Syndrome, Type 3	Axenfeld-Rieger Syndrome 3
Axenfeld Anomaly	Rieger Anomaly
Rieger Syndrome	Rieger Eye Malformation Sequence

Pulmonary Neuroendocrine Tumor

Neuroendocrine Neoplasm Of Lung

Axenfeld-Rieger Syndrome

Axenfeld Syndrome	Rieger Syndrome
Rieger Anomaly	Axenfeld Anomaly
Anomaly, Rieger'S	Hagedoom Syndrome
Rgs - Rieger Syndrome	Rieger'S Anomaly
Goniodysgenesis Hypodontia	Iridogoniodysgenesis With Somatic Anomalies
Ars	Axenfeld And Rieger Anomaly
Axra	Axrs
Rieger Eye Malformation Sequence

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09868	OTP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	OTP	VGNC	VGNC:44182
Mus musculus	OTP	MGD	MGI:99835
Macaca mulatta	OTP	VGNC	VGNC:84457
Rattus norvegicus	OTP	RGD	RGD:727945
Felis catus	OTP	VGNC	VGNC:102277
Bos taurus	OTP	VGNC	VGNC:55130