Kcnmb1 - potassium calcium-activated channel subfamily M regulatory beta subunit 1 Gene

Also Known as BKbeta; BKbeta1; slo-beta; slo-beta-1; k(VCA)beta-1

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 29747

Summary

Enables Potassium Channel regulator activity. Involved in several processes, including cellular response to bile acid; cellular response to ethanol; and cellular response to hypoxia. Predicted to be integral component of membrane. Predicted to be part of voltage-gated Potassium Channel complex. Used to study hypertension. Biomarker of hypertension and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnmb1 Products (1)

mRNA Protein Name
NM_019273.1 NP_062146.1 calcium-activated potassium channel subunit beta-1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables potassium channel regulator activity IDA
IDA: Inferred from direct assay
9888999 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in cellular response to bile acid IDA
IDA: Inferred from direct assay
22123969 RGD
involved in cellular response to ethanol IDA
IDA: Inferred from direct assay
19616547 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
19461047 RGD
involved in positive regulation of potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
23455312 RGD
involved in response to calcium ion IDA
IDA: Inferred from direct assay
9888999 RGD
involved in vasodilation IDA
IDA: Inferred from direct assay
23455312 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-activated potassium channel subunit beta-1

  • BK channel subunit beta-1

  • calcium-activated potassium channel beta subunit

  • calcium-activated potassium channel subunit beta

  • calcium-activated potassium channel, subfamily M subunit beta-1

  • charybdotoxin receptor subunit beta-1

  • maxi K channel subunit b

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Rare Diseases
HY-W396714 Succinic acid sodium Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS07165 KCNMB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Kcnmb1 NCBI NCBI:3779