Sh2d3c - SH2 domain containing 3C Gene

Also Known as Chat; Nsp3; Shep1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27387

Summary

Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Predicted to act upstream of or within signal transduction. Predicted to be located in cell projection; cytoplasm; and plasma membrane. Orthologous to human SH2D3C (SH2 domain containing 3C). [provided by Alliance of Genome Resources, Apr 2022]

Sh2d3c Products (9)

mRNA Protein Name
NM_001252547.2 NP_001239476.1 SH2 domain-containing protein 3C isoform 2
NM_001412517.1 NP_001399446.1 SH2 domain-containing protein 3C isoform 3
NM_001412518.1 NP_001399447.1 SH2 domain-containing protein 3C isoform 3
NM_001412519.1 NP_001399448.1 SH2 domain-containing protein 3C isoform 3
NM_001412520.1 NP_001399449.1 SH2 domain-containing protein 3C isoform 4
NM_001412521.1 NP_001399450.1 SH2 domain-containing protein 3C isoform 5
NM_001412522.1 NP_001399451.1 SH2 domain-containing protein 3C isoform 6
NM_001412523.1 NP_001399452.1 SH2 domain-containing protein 3C isoform 7
NM_013781.4 NP_038809.1 SH2 domain-containing protein 3C isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20956287 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH2 domain-containing protein 3C

  • Cas/HEF1-associated signal transducer

  • SH2 domain-containing Eph receptor-binding protein 1

  • novel SH2-containing protein 3

Sh2d3c Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Sh2d3c Q9QZS8 Nedd9 Mus musculus O35177
Anti Bait CoIP
20956287
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12824 SH2D3C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh2d3c NCBI NCBI:10044