106083-71-0
106083-71-0
Chemical Structure
Radafaxine hydrochloride
Synonym(s): (S,S)-Hydroxybupropion hydrochloride; GW-353162A; BW-306U
- CAS No.: 106083-71-0
- Formula:C13H19Cl2NO2
- Molecular Weight:292.20
IUPAC Name: (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol hydrochloride
InChIKey: ORXTVTDGPVINDN-BTJVGWIPSA-N
SMILES: O[C@]1(C2=CC=CC(Cl)=C2)[C@H](C)NC(C)(C)CO1.[H]Cl
Biological Activity:
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Radafaxine hydrochloride | 98.92% | Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. | ||||||||||||||||||||
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References
- Xu H, et al. Stereoselective analysis of hydroxybupropion and application to drug interaction studies. Chirality. 2007 Mar;19(3):163-70. [Content Brief]
- Volkow ND, et al. The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects. Biol Psychiatry. 2005 Mar 15;57(6):640-6. [Content Brief]
- Bondarev ML, et al. Behavioral and biochemical investigations of bupropion metabolites. Eur J Pharmacol. 2003 Aug 1;474(1):85-93. [Content Brief]
Keywords
