3048537-58-9

HPK1-IN-55 Chemical Structure
3048537-58-9

Chemical Structure

HPK1-IN-55

  • CAS No.: 3048537-58-9
  • Formula:C30H34N8O3
  • Molecular Weight:554.64

InChIKey: IKGOYMIPWBVCQZ-UHFFFAOYSA-N

SMILES: COC1=CC(NC2=CC=C3C4(N(CC3=N2)C)CCN(CC4)C5COC5)=C(N=C1C6=C(C7=CC=C6)N=CN7C)C(N)=O

Biological Activity: HPK1-IN-55 (compound 19) is a selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <0.51 nM. HPK1-IN-55 shows excellent kinase selectivity (>637-fold vs GCK-like kinase and >1022-fold vs LCK). HPK1-IN-55 has anticancer effects[1].

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-170365 		HPK1-IN-55 HPK1-IN-55 (compound 19) is a selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <0.51 nM. HPK1-IN-55 shows excellent kinase selectivity (>637-fold vs GCK-like kinase and >1022-fold vs LCK). HPK1-IN-55 has anticancer effects.
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