33245-39-5
Chemical Structure
Fluchloralin
- CAS No.: 33245-39-5
- Formula:C12H13ClF3N3O4
- Molecular Weight:355.70
IUPAC Name: N-(2-chloroethyl)-2,6-dinitro-N-propyl-4-(trifluoromethyl)aniline
InChIKey: MNFMIVVPXOGUMX-UHFFFAOYSA-N
SMILES: ClCCN(CCC)C1=C(C=C(C(F)(F)F)C=C1[N+]([O-])=O)[N+]([O-])=O
Biological Activity: Fluchloralin is a dinitroaniline herbicide that effectively controls annual gramineous and broadleaf weeds primarily by inhibiting tubulin synthesis and cell division. Fluchloralin exhibits cytotoxicity and genotoxicity, and promotes cell apoptosis by activating apoptotic signaling proteins, forming DNA ladder bands, inducing cell shrinkage and nuclear fragmentation[1][2].
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Fluchloralin | Fluchloralin is a dinitroaniline herbicide that effectively controls annual gramineous and broadleaf weeds primarily by inhibiting tubulin synthesis and cell division. Fluchloralin exhibits cytotoxicity and genotoxicity, and promotes cell apoptosis by activating apoptotic signaling proteins, forming DNA ladder bands, inducing cell shrinkage and nuclear fragmentation. | |||||||||||||||||||||
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- [1]. Hong T, et al. Fluchloralin induces developmental toxicity in heart, liver, and nervous system during early zebrafish embryogenesis. Comp Biochem Physiol C Toxicol Pharmacol. 2023;271:109679. [Content Brief]
- [2]. Sinha S, et al. Fluchloralin is cytotoxic and genotoxic and induces apoptosis in mammalian cells. Environ Mol Mutagen. 1998;31(3):257-262. [Content Brief]
Keywords
