5 Results for "

COPA

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "COPA" in MCE Product Catalog:

Cat. No.: HY-P10914
CAS No.: 1426227-11-3
Target:  

MDM-2/p53 Autophagy

연구분야:  

Inflammation/Immunology Cancer

D-CopA3 is the inhibitor for MDM2 and the activator for p53 signaling pathway. D-CopA3 exhibits cytotoxicity in colorectal cancer cells HCT-116, LoVo, and RKO (IC50=15-18 μM), induces JNK/Beclin-1 mediated autophagy. D-CopA3 downregulates the expression of cell cycle inhibitory protein p21Cip1/Waf1, enhances the mucosal barrier function and reduces penetration of inflammatory mediators. D-CopA3 exhibits anti-inflammtory activity in mouse C. difficile toxin A-induced acute enteritis models and DSS (HY-116282)-induced chronic colitis models. D-CopA3 exhibits antitumor efficacy in mouse HCT-116 xenograft models .
Cat. No.: HY-RS03021
연구분야:  

Others

COPA Human Pre-designed siRNA Set A contains three designed siRNAs for COPA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS19588
연구분야:  

Others

Copa Mouse Pre-designed siRNA Set A contains three designed siRNAs for Copa gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS26085
연구분야:  

Others

Copa Rat Pre-designed siRNA Set A contains three designed siRNAs for Copa gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P82360
Synonyms: Alpha COP; Alpha COPI; AlphaCOP; COP A; COPA; HEP COP; Proxenin; Xenin

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat