5 Results for "

Cav1.1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Cav1.1" in MCE Product Catalog:

製品番号: HY-P3269
CAS 番号: 178805-91-9
Target:  

Calcium Channel

研究分野:  

Cardiovascular Disease

Calciseptine is a natural polypeptide toxin found in the venom of the black mamba snake (Dendroaspis p. polylepis). Calciseptine is a highly effective and selective blocker of the L-type channel of the Cav1.2 subtype, with an IC50 value of 92 nM. Calciseptine has no effect on Cav3.1, Cav2.2, Cav2.1, Cav1.1, voltage-sensitive sodium channels and potassium channels. Calciseptine exhibits negative inotropic and negative relaxant effects on mice, and does not affect heart rate or the action potential of sinoatrial node pacemaker cells. Calciseptine can be used for research on cardiovascular diseases[1].
製品番号: HY-RS21234
研究分野:  

Others

Cacna1s Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cacna1s gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

製品番号: HY-RS01800
研究分野:  

Others

CACNA1S Human Pre-designed siRNA Set A contains three designed siRNAs for CACNA1S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

製品番号: HY-122552
CAS 番号: 108853-09-4
Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin (HY-17394) .
製品番号: HY-P10332
Target:  

ペプチド

研究分野:  

Others

WL 47 dimer (ligand 1) is a caveolin-1 (CAV-1) ligand with high affinity, selectivity and oligomer dissociation activity. WL 47 dimer simultaneously occupies two binding sites of CAV-1, inducing the dissociation of oligomers. WL 47 dimer has 7500-fold improved affinity compared to its T20 parent ligand and an 80% decrease in sequence length. WL 47 dimer can be used to permit targeted study of CAV-1 function .