2 Results for "

PKC412-13C6

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PKC412-13C6" in MCE Product Catalog:

  • Targets Recommended:
O-Desmethyl midostaurin-13C6
O-Desmethyl midostaurin-13C6
0 Images
Cat. No.: HY-W751181
Synonyms: CGP62221-13C6; O-Desmethyl PKC412-13C6
O-Desmethyl midostaurin- 13C6 (CGP62221- 13C6; O-Desmethyl PKC412- 13C6) is the 13C-labeled O-Desmethyl Midostaurin (HY-129491). O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo . Midostaurin is a multi-targeted protein kinase inhibitor?with?IC50?ranging from 22-500 nM.
Midostaurin-13C6
Midostaurin-13C6
0 Images
Cat. No.: HY-W751179
Synonyms: PKC412-13C6; CGP 41251-13C6
Midostaurin- 13C6 (PKC412- 13C6) is the 13C-labeled Midostaurin (HY-10230). Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM . Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects .
Assay Types