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Tibsovo

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20
20 Cited Publications
Cat. No.: HY-18767
CAS No.: 1448347-49-6
Synonyms: AG-120
Research Areas:  

Metabolic Disease Cancer

Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity .