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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
USP53
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "USP53" in MCE Product Catalog:
Art. -Nr.: HY-RS15564
Target:
Forschungsgebiete:
USP53 Human Pre-designed siRNA Set A contains three designed siRNAs for USP53 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS27023
Target:
Forschungsgebiete:
Usp53 Rat Pre-designed siRNA Set A contains three designed siRNAs for Usp53 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS20514
Target:
Forschungsgebiete:
Usp53 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Usp53 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-184244
CAS. Nr.: 3094094-17-1
Synonyms: CAS-13312-010
Target:
Forschungsgebiete:
CAS-010 (CAS-13312-010) is a potent and selective USP28 inhibitor with an IC50 of 2.2 nM against full-length USP28. CAS-010 acts as a ubiquitin-competitive inhibitor and shows higher selectivity over USP25 (IC50 = 51 nM) and other USP family members, disrupting the 53BP1-USP28 interaction and suppressing p53-dependent transcription of CDKN1A (p21), MDM2, and BAX. CAS-010 can be used for studying USP28-mediated DNA damage response and p53 signaling in cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
