4 Results for "

af802

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "af802" in MCE Product Catalog:

44
Alectinib Hydrochloride
Alectinib Hydrochloride
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44 Cited Publications
Cat. No.: HY-13011A
CAS No.: 1256589-74-8
Pureté:  99.92%
Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; af-802 Hydrochloride
Target:  

Anaplastic lymphoma kinase (ALK)

Domaines de recherche:  

Neurological Disease Cancer

Alectinib (CH5424802; RO5424802; RG7853) Hydrochloride is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
Alectinib Hydrochloride (Standard)
Alectinib Hydrochloride (Standard)
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Cat. No.: HY-13011AR
CAS No.: 1256589-74-8
Synonyms: CH5424802 Hydrochloride (Standard); RO5424802 Hydrochloride (Standard); af-802 Hydrochloride (Standard)
Target:  

Anaplastic lymphoma kinase (ALK) Reference Standards

Domaines de recherche:  

Cancer

Alectinib (Hydrochloride) (Standard) is the analytical standard of Alectinib (Hydrochloride). This product is intended for research and analytical applications. Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
Alectinib-d8
Alectinib-d8
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Cat. No.: HY-13011S
CAS No.: 1256585-15-5
Synonyms: CH5424802-d8; RO5424802-d8; af802-d8
Alectinib-d8 is the deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
Alectinib-d6
Alectinib-d6
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Cat. No.: HY-13011S1
CAS No.: 1616374-19-6
Pureté:  98.05%
Synonyms: CH5424802-d6; RO5424802-d6; af802-d6
Alectinib-d6 is deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively . Alectinib demonstrates effective central nervous system (CNS) penetration .
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