1 Result for "

braf+protac

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "braf+protac" in MCE Product Catalog:

Cat. No.: HY-137488
CAS No.: 2417296-82-1
Target:  

PROTACs Raf

Research Areas:  

Cancer

PROTAC BRAF-V600E degrader-2 (compound 12) is a potent BRAF-V600E degrader with Kds of 14.4 nM and 9.5 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-2 selectively degraded the kinase domain of BRAF-V600E but not the wild-type BRAF. PROTAC BRAF-V600E degrader-2 inhibits melanoma cell growth .