6 Results for "

mitotane

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "mitotane" in MCE Product Catalog:

6
Cucurbitacin E
Cucurbitacin E
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6 Cited Publications
Art. -Nr.: HY-N0417
CAS. Nr.: 18444-66-1
Synonyms: α-Elaterin; α-Elaterine
Category:  

Triterpenes Terpenoids Cucurbitaceae Plants Disease Research Fields Cancer

Target:  

CDK Autophagy PANoptosis

Cucurbitacin E is a CDK1 inhibitor that significantly inhibits the activity of the cyclin B1/CDC2 complex. Cucurbitacin E also induces PANoptosis in adrenocortical carcinoma cells in a ZBP1-dependent manner. Cucurbitacin E exhibits synergistic effects with Mitotane (HY-13690); when used in combination, they effectively eliminate tumors .
5
Mitotane
Mitotane
0 Images
5 Cited Publications
Art. -Nr.: HY-13690
CAS. Nr.: 53-19-0
Reinheit:  99.92%
Synonyms: 2,4′-DDD; o,p'-DDD
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Mitotane (Standard)
Mitotane (Standard)
0 Images
Art. -Nr.: HY-13690R
CAS. Nr.: 53-19-0
Synonyms: 2,4′-DDD (Standard); o,p'-DDD (Standard)
Target:  

Reference Standards Apoptosis

Forschungsgebiete:  

Cancer

Mitotane (Standard) is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Mitotane-13C6
Mitotane-13C6
0 Images
Art. -Nr.: HY-13690S1
CAS. Nr.: 1261396-21-7
Reinheit:  98.62%
Synonyms: 2,4′-DDD-13C6; o,p'-DDD-13C6
Mitotane- 13C6 is the 13C labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Mitotane-13C12
Mitotane-13C12
0 Images
Art. -Nr.: HY-13690S3
CAS. Nr.: 2483736-36-1
Synonyms: 2,4′-DDD-13C12; o,p'-DDD-13C12
Mitotane- 13C12 (2,4′-DDD- 13C12) is 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Mitotane-d8
Mitotane-d8
0 Images
Art. -Nr.: HY-13690S2
CAS. Nr.: 2673270-14-7
Synonyms: 2,4′-DDD-d8; o,p'-DDD-d8
Mitotane-d8 is the deuterium labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Assay Types