1 Result for "

ru521

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ru521" in MCE Product Catalog:

83
83 Cited Publications
製品番号: HY-114180
CAS 番号: 2262452-06-0
純度:  99.95%
別名: ru320521
研究分野:  

Metabolic Disease

RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) .