25915-57-5
Chemical Structure
Sucrose dilaurate
- CAS No.: 25915-57-5
- Formula:C36H66O13
- Molecular Weight:706.90
InChIKey: JQFGWTGICMGFGX-SDBGFSJOSA-N
SMILES: O=C(CCCCCCCCCCC)OC[C@]1(O[C@@H]([C@H]([C@@H]1OC(CCCCCCCCCCC)=O)O)CO)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Biological Activity: Sucrose dilaurate acts as an emulsifier, dispersant and stabilizer. Sucrose dilaurate reduces the release of HMGB1 from UVB-irradiated keratinocytes. Sucrose dilaurate inhibits melanogenesis and decreases bilirubin levels. Sucrose dilaurate induces autophagy in human epidermal keratinocytes, thereby reducing carboxymethyl lysine (CML) levels. Sucrose dilaurate reduces the secretion of insulin-like growth factor-binding protein 3 (IGFBP3) and nerve growth factor (NGF) by senescent keratinocytes. Sucrose dilaurate is investigated as an emulsifier, dispersant or stabilizer in the cosmetics, food and pharmaceutical industries[1][2][3][4].
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Sucrose dilaurate | Sucrose dilaurate acts as an emulsifier, dispersant and stabilizer. Sucrose dilaurate reduces the release of HMGB1 from UVB-irradiated keratinocytes. Sucrose dilaurate inhibits melanogenesis and decreases bilirubin levels. Sucrose dilaurate induces autophagy in human epidermal keratinocytes, thereby reducing carboxymethyl lysine (CML) levels. Sucrose dilaurate reduces the secretion of insulin-like growth factor-binding protein 3 (IGFBP3) and nerve growth factor (NGF) by senescent keratinocytes. Sucrose dilaurate is investigated as an emulsifier, dispersant or stabilizer in the cosmetics, food and pharmaceutical industries. | |||||||||||||||||||||
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- [1]. Wang J, et al. The combination of sucrose dilaurate and sucrose laurate suppresses HMGB1: an enhancer of melanocyte dendricity and melanosome transfer to keratinocytes. J Eur Acad Dermatol Venereol. 2022;36 Suppl 3:3-11. [Content Brief]
- [2]. Fang B, et al. A Potential Role of Keratinocyte-Derived Bilirubin in Human Skin Yellowness and Its Amelioration by Sucrose Laurate/Dilaurate. Int J Mol Sci. 2022;23(11):5884. Published 2022 May 24. [Content Brief]
- [3]. Laughlin T, et al. Autophagy activators stimulate the removal of advanced glycation end products in human keratinocytes. J Eur Acad Dermatol Venereol. 2020;34 Suppl 3:12-18. [Content Brief]
- [4]. Hakozaki T, et al. Over-Represented Senescent Keratinocytes in Hyperpigmented Spots Promote Melanocyte Activation via IGFBP3 and NGF. Int J Mol Sci. 2025;26(21):10724. Published 2025 Nov 4. [Content Brief]
Keywords
