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Art. -Nr.: HY-168103

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FBPase-IN-3

FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC₅₀ of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis.

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CAS. Nr.: 3102011-46-8
Formel: C₂₁H₁₆ClN₃O₄S
Molecular Weight:441.89

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

FBPase-IN-3 Chemical Structure

CAS. Nr.: 3102011-46-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC₅₀ of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis^[1].

Chemical Information

CAS. Nr. 3102011-46-8
Molecular Weight 441.89
Formel C₂₁H₁₆ClN₃O₄S
SMILES

O=C(NS(=O)(C1=CC=C(OC)C=C1)=O)C2=CC(Cl)=CC(C3=NC4=CC=CC=C4N3)=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Huahao Wang, et al. Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model. Eur J Med Chem. 2024 Sep 19:279:116888. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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