Lgi4 - leucine-rich repeat LGI family, member 4 Gene

Also Known as clp; Lgil3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243914

Summary

Involved in regulation of myelination. Acts upstream of or within adult locomotory behavior and neurogenesis. Located in extracellular space. Is expressed in several structures, including adipose tissue; alimentary system; nervous system; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-1 and childhood absence epilepsy. Orthologous to human LGI4 (leucine rich repeat LGI family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Lgi4 Products (1)

mRNA Protein Name
NM_144556.2 NP_653139.2 leucine-rich repeat LGI family member 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
20220021 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within Schwann cell development IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
1652607 MGI
acts upstream of or within glial cell development IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within glial cell proliferation IDA
IDA: Inferred from direct assay
21068328 MGI
acts upstream of or within gliogenesis IGI
IGI: Inferred from genetic interaction
21068328 MGI
acts upstream of or within gliogenesis IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within myelination IDA
IDA: Inferred from direct assay
16341215 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
15282162 MGI
acts upstream of or within myelination in peripheral nervous system IMP
IMP: Inferred from mutant phenotype
1652607 MGI
acts upstream of or within neuron maturation IMP
IMP: Inferred from mutant phenotype
15282162 MGI
involved in regulation of myelination IDA
IDA: Inferred from direct assay
16341215 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular space IDA
IDA: Inferred from direct assay
16341215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat LGI family member 4

  • LGI1-like protein 3

  • leucine-rich glioma inactivated protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS07616 LGI4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16306 Lgi4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lgi4 NCBI NCBI:163175