Fzd3 - frizzled class receptor 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266715

Summary

Predicted to enable PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Involved in brain development; response to electrical stimulus; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including apical plasma membrane; filopodium tip; and lateral plasma membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Predicted to colocalize with presynaptic active zone. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome and schizophrenia. Orthologous to human FZD3 (Frizzled class receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Fzd3 Products (1)

mRNA Protein Name
NM_153474.1 NP_703204.1 frizzled-3 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
16258230 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16258230 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

frizzled-3

  • frizzled family receptor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05179 FZD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05185 FZD9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fzd3 NCBI NCBI:7976
Mus musculus Fzd3 NCBI NCBI:14365